Knucklehead is a comedy film starring WWE Superstar Big Show. Its was released on October 22, 2010 in select theatres.

The film centers on a fight promoter deeply in debt to his crooked rival. Desperate for a new fighter that will help him win back everything he owes, the promoter catches a break when a 450-pound church handyman who has spent his entire life in an orphanage agrees to wrestle on behalf of his fellow orphans.